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Project Title

Heart to Health

Funding Dates



Heart to Health LogoHeart to Health combined two previously tested and effective lifestyle and medication interventions (one web-based and one counselor-based) to reduce cardiovascular disease (CVD) risk and tested this intervention in a diverse group of patients cared for at family practices in North Carolina. Using a comparative effectiveness research framework, these intervention formats were compared for their impact on estimated CVD risk reduction and other important outcomes to key clinical and public health stakeholders (patients, payers, and decision makers). The primary outcome was a reduction in the estimated 10-year risk of coronary heart disease as determined by the Framingham equation. Changes in dietary intake, physical activity, blood pressure, blood lipids, and medication use, in addition to feasibility, acceptability and cost, were important secondary outcomes.

Research Areas 

Cardiovascular Health, Obesity, and Diabetes
Nutrition and Physical Activity

Principal Investigator

Thomas C. Keyserling, MD, MPH


Center for Disease Control and Prevention